Table 3. Ergothioneine concentration in mouse cultured cortical NPCs exposed to ERGO (500 µM) for 6 and 9 days.
Ergothioneine concentration (µg/g protein)a) | |
NPCs (6DIV, (−) ERGO) | <61 |
NPCs (6DIV, (+)ERGO) | 3572±629 [0.0016 mol/L]b) |
NPCs (9DIV, (−)ERGO) | <61 |
NPCs (9DIV, (+)ERGO) | 10687±693# [0.0047 mol/L]b) |
a) Concentration of ergothioneine was measured by LC-MS/MS.
b) The values shown in [ ] represent the mean values for intracellular concentration of ERGO estimated based on an assumption that cellular volume per g protein is 10 mL.
P<0.01, significant difference from the corresponding value at 6 DIV.