Figure 1. Pharmacological agents hindering 5HT neurotransmission affect locomotion in fly larvae.

Canton-S flies were treated for 1 hr with α-methyl-L-Dopa (1 mM), Fluoxetine (100 µM) and MDMA (1 mM). After drug treatment, larval locomotion was evaluated. Data shown represent mean distance+SEM covered by n = 14 or more animals over 140 sec; * indicate p<0.05 compared to control Canton-S flies, ANOVA followed by Tukey post-hoc.