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. 2014 Feb 25;9(2):e89748. doi: 10.1371/journal.pone.0089748

Figure 4. SF-E inhibits IFNγ-induced activation of ERK1/2 in BV-2 microglial cells.

Figure 4

(A) Western blot analysis showing a representative experiment of SF-E pretreatment on IFNγ-induced ERK1/2 phosphorylation in BV-2 microglial cells. Cells were treated with SF-E (0 to 80 µg/mL) for 1 h followed by stimulation with IFNγ (10 ng/mL) for 8 h. (B) Bar graphs representing p-ERK1/2/ERK1/2 ratios using IFNγ as control (100%). Results are expressed as the mean ± SEM (n = 5) and were analyzed by one-way ANOVA followed by Dunnett’s tests, *p<0.05; **p<0.01.