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. 2014 Feb 25;9(2):e89796. doi: 10.1371/journal.pone.0089796

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© 2014 Xie et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) The ThT fluorescence of Tau 0N4R isoform (circles), Tau 0N3R isoform (squares), and MAP2c (triangles) aggregates were measured at the times indicated. (B) After the 7-day incubation, the amount of Sarkosyl-insoluble proteins in the indicated samples was analyzed by SDS-PAGE followed by Coomassie brilliant blue staining.