Skip to main content
. 2014 Feb 25;9(2):e90187. doi: 10.1371/journal.pone.0090187

Figure 6. Enhancement of crosslinking-induced dispersal of aneural AChR clusters by synaptogenic stimulation.

Figure 6

A, Representative images showing the effects of synaptogenic signals on the dispersal of aneural AChR clusters triggered by BBQ crosslinking. The aneural AChR clusters (arrows) were counted in cultured muscle cells in the presence or absence of BBQ crosslinking, in combination with agrin treatment (middle 2 columns) or HB-GAM bead stimulation (last 2 columns). B, Quantification showing the synergistic action of AChR crosslinking and synaptogenic signaling on the dispersal of aneural AChR clusters. Data are mean ± SEM; *p<0.01 (Student’s t test).