Table 1.
Clinical indices of pregnancies
| Variable | Preeclampsia (n = 19) | Normal pregnancy (n = 29) | Nonpregnant controls (n = 19) | ANOVA P values |
|---|---|---|---|---|
| Age, years1 | 34 (21–40) | 33 (26–40) | 31 (24–45) | P = 0.22 |
| Pregnancy, weeks1 | 33 (25–40)2 | 38 (24–40) | – | – |
| Systolic pressure, mmHg3 | 139±34,5 | 111±2 | 111±2 | P < 0.0001 |
| Diastolic pressure, mmHg3 | 87±34,5 | 72±1 | 69±1 | P < 0.0001 |
| Body mass index, kg/m2 | 21.5±0.6 | 22.5±0.5 | 22.4±0.6 | P = 0.46 |
| Stiffness index, m/s | 8.4±0.62,6 | 7.2±0.2 | 6.9±0.3 | P = 0.01 |
| Reflection index, % | 64.7±2.84 | 51.4±1.75 | 61.5±1.8 | P < 0.0001 |
| Proteinuria (24h), mg1 | 1300 (300–15000)4,5 | 45 (10–150) | 25 (10–75) | P < 0.0001 |
| Hematocrit, % | 34.4±0.85 | 34.4±0.65 | 39.7±0.5 | P < 0.0001 |
| Platelets, cells/mm3 | 240,000(133,000–476,000)6 | 276,000(88,000–458,000) | 309,000(216,000–437,000) | P < 0.01 |
| C-reactive protein, mg/L | 4.21±1.105 | 3.16±0.536 | 0.96±0.17 | P < 0.01 |
| Plasma creatinine, mg/dL | 0.70±0.024 | 0.55±0.025 | 0.70±0.02 | P < 0.0001 |
| Creatinine clearance, mL/min | 108.8±5.84 | 141.2±8.36 | 114.8±5.7 | P = 0.01 |
| Plasma uric acid, mg/dL | 5.9±0.34,5 | 4.1±0.2 | 3.9±0.2 | P < 0.0001 |
| Plasma glucose, mg/dL | 86.0±4.1 | 77.9±1.86 | 86.8±1.3 | P < 0.05 |
| Plasma cholesterol, mg/dL | 262.4±14.45 | 276.2±12.25 | 183.5±8.7 | P < 0.0001 |
| Plasma triglycerides, mg/dL | 277.6±22.05 | 225.9±16.55 | 65.5±5.2 | P < 0.0001 |
Data are mean ± SEM, unless otherwise noted.
1Data are median (range); P < 0.05 vs. 2normal pregnancy or vs. 6control.
3Blood pressure values of preeclamptic patients are those recorded at the time of delivery after pharmacological intervention. The values on which diagnosis of preeclampsia was based were higher at the time of hospital admission: systolic blood pressure 155 (140–170) mmHg, diastolic blood pressure 100 (90–110 mmHg).
P < 0.01 vs. 4normal pregnancy or vs. 5controls.
Abbreviation: ANOVA, analysis of variance.