Table 1.

Clinical characteristics of patients with essential (EHT) or renovascular (RVHT) hypertension

Characteristic	EHT (n = 75)	RVHT (n = 69)	P value
Age, y	65 (50–75)	69 (52–75)	0.003
Sex, male/female	41/34	32/37	0.32
Body mass index, kg/m2	29±6	30±6	0.19
Race, white/other/unknown	72/1/2	63/1/5	0.30
Duration of follow-up, y	8.8 (2–9.1)	8.8 (1.1–9.1)	0.35
Systolic blood pressure, mm Hg	129±23	147±23	<0.0001
Diastolic blood pressure, mm Hg	72±14	76±13	0.08
Mean arterial pressure, mm Hg	91±16	100±14	0.0007
Heart rate, bpm	66±12	68±13	0.50
Total cholesterol, mg/dl	169 (27–313)	162 (88–382)	0.79
Hemoglobin, g/dl	14±2	13±1	0.13
Comorbidities
Diabetes mellitus	15 (20%)	27 (39%)	0.01
Coronary artery disease	36 (48%)	38 (55%)	0.40
Family history of coronary artery disease	42 (57%)	40 (59%)	0.88
Smoking status			0.003
Current smoker	18 (24%)	3 (4%)
Former smoker	35 (47%)	45 (66%)
Nonsmoker	21 (28%)	20 (29%)
Recent myocardial infarction/stroke	6 (8%)	5 (7%)	0.86
Coronary artery bypass grafting	11 (15%)	18 (26%)	0.09
Atrial fibrillation	15 (20%)	12 (17%)	0.69
Sleep apnea	17 (23%)	19 (27%)	0.50
Cardiovascular medications
Antihypertensive	3 (0–6)	3 (0–7)	0.03
Diuretics	48 (64%)	50 (72%)	0.28
Calcium channel blockers	21 (28%)	29 (42%)	0.08
Beta-blockers	57 (76%)	53 (77%)	0.91
Angiotensin-converting enzyme inhibitors	26 (35%)	30 (43%)	0.28
Angiotensin receptor blockers	14 (19%)	20 (30%)	0.14
Alpha-blockers	8 (11%)	6 (9%)	0.69
Statins	37 (50%)	47 (68%)	0.03
Hormone replacement therapy	5 (7%)	3 (4%)	0.54
Renal function
Serum creatinine, mg/dl	1 (0.5–1.9)	1.2 (0.6–5.1)	<0.0001
eGFR-MDRD, ml/min/1.73/m2	72 (34–143)	49 (11–101)	<0.0001
Proteinuria, mg/24h	128 (23–1584)	152 (27–1583)	0.48
Systemic plasma renin activity, ng/ml/ha	0.6 (0.6–9.9)	1 (0.6–22)	0.03

Data are presented as median (range), number (%), or mean ± SD, as appropriate.

Abbreviation: eGFR-MDRD, estimated glomerular filtration rate–modification of diet in renal disease.

^aAvailable for 18 (24%) and 27 (39%), of EHT and RVHT patients, respectively.