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. 2014 Feb;33(2):115–122. doi: 10.5732/cjc.012.10236

Table 3. Cytotoxic effects of temozolomide (TMZ) and MG-132 alone or in combination on MGMT-positive GSC lines and the parental glioma cell lines.

Cell line Growth inhibition rate (%)
TMZ MG-132 TMZ plus MG-132
U251 48.04 ± 1.00 15.49 ± 2.12 60.65 ± 2.49
U251G 17.48 ± 2.24 19.12 ± 4.27 62.99 ± 1.07
SKMG-4 45.06 ± 2.46 16.52 ± 4.73 57.28 ± 8.35
SKMG-4G 20.44 ± 2.95 20.69 ± 3.84 60.87 ± 4.87
SKMG-1 42.39 ± 1.60 15.41 ± 1.63 54.12 ± 2.07
SKMG-1G 19.33 ± 4.07 16.69 ± 1.79 57.02 ± 1.53
SF295 43.72 ± 2.62 16.30 ± 4.49 55.43 ± 4.35
SF295G 19.18 ± 0.68 19.08 ± 3.18 57.37 ± 3.20
U87 45.43 ± 2.97 21.08 ± 1.72 62.38 ± 3.11
U87G 21.16 ± 1.26 24.45 ± 2.12 33.94 ± 1.50

TMZ, temozolomide; GSC, glioma stem-like cell. Data are presented as mean ± standard deviation (SD) of 3 repeated experiments.