Figure 4. Comparison between tobacco cigarette and electronic cigarette devices in plasma nicotine levels.

Data for tobacco cigarette was derived from Vansickel et al⁷. Nicotine levels after smoking a tobacco cigarette in 5 minutes (18.8 ng/ml) are 185% and 286% higher compared to using the first and new-generation electronic cigarette device respectively. Additionally, plasma nicotine levels after smoking one tobacco cigarette are almost equal to the values after using the new-generation device for 35 minutes (18.52 ng/ml), while they are 73% higher compared to the values after using the first-generation device for 35 minutes (10.88 ng/ml).