Table 2.
Total | Chest Pain | DCM | Liver cirrhosis |
ANOVA p value |
||
---|---|---|---|---|---|---|
n | 27 | 10 | 8 | 9 | - | |
Heart Rate (bpm) | 72 ± 14 | 70 ± 10 | 83 ± 17 | 66 ± 12 | - | |
Catheterization Data | ||||||
Mean Arterial Pressure (mm Hg) | 98 ± 19 | 102 ± 11 | 110 ± 20 | 82 ± 13* | 0.001 | |
dP/dtmax (mm Hg s−1) | 1283 ± 327 | 1529 ± 242 | 957 ± 231* | 1216 ± 212* | <0.001 | |
Cardiac Output (l/min) | 6.9 ± 2.4 | 6.2 ± 1.5 | 5.5 ± 1.5 | 8.9 ± 2.7* | 0.003 | |
Cardiac Index (l/min/m2) | 4.0 ± 1.2 | 3.9 ± 0.8 | 3.2 ± 0.8 | 4.8 ± 1.4 | 0.04 | |
Right Atrial Pressure (mm Hg) | 10 ± 4 | 8 ± 4 | 8 ± 5 | 12 ± 2* | <0.001 | |
Mean Pulmonary Pressure (mm Hg) | 24 ± 6 | 23 ± 5 | 27 ± 9 | 21 ± 6 | 0.5 | |
Pulmonary Capillary Wedge Pressure (mm Hg) | 15 ± 5 | 13 ± 3 | 17 ± 6 | 16 ± 5 | 0.4 | |
Pulmonary Vascular Resistance (dyn·cm·s−5) | 120 ± 69 | 137 ± 49 | 159 ± 66 | 57 ± 48* | 0.005 | |
Systolic Chamber Function | ||||||
Emax (mm Hg/ml) | 2.8 ± 1.0 | 3.1 ± 0.8 | 2.1 ± 0.7* | 3.2 ± 1.1 | 0.04 | |
Preload | ||||||
End-Diastolic LV Volume (ml) | 114 ± 46 | 88 ± 24 | 162 ± 49* | 102 ± 34 | 0.003 | |
End-Diastolic LV Pressure (mm Hg) | 20 ± 7 | 18 ± 4 | 21 ± 10 | 20 ± 7 | 0.9 | |
Preload Index | 0.0 ± 1.2 | −0.6 ± 0.6 | 0.9 ± 1.4* | −1.3 ± 1.1 | 0.03 | |
Afterload | ||||||
End-Systolic Wall Stress (mm Hg) | 348 ± 117 | 347 ± 76 | 454 ± 120* | 257 ± 68* | <0.001 | |
Effective Arterial Elastance (mm Hg/ml) | 1.5 ± 0.7 | 1.6 ± 0.3 | 2.2 ± 0.7* | 0.9 ± 0.3* | <0.001 | |
Systemic Vascular Resistance (dyn·cm·s−5) | 1191 ± 589 | 1301 ± 400 | 1624 ± 659 | 683 ± 273* | 0.001 | |
Afterload Index | 0.0 ± 1.7 | 0.2 ± 0.9 | 1.5 ± 1.7* | −1.5 ± 0.7* | <0.001 | |
Chamber Remodeling | ||||||
End-Systolic Volume (ml) | 51 ± 38 | 28 ± 13 | 99 ± 37* | 35 ± 11 | <0.001 | |
LV Mass (g) | 140 ± 52 | 109 ± 17 | 184 ± 74* | 134 ± 21 | 0.005 | |
Noninvasive Systolic Chamber Function | ||||||
Ejection Fraction (%) | 54 ± 20 | 65 ± 7 | 26 ± 9* | 65 ± 8 | <0.001 | |
Mid-Wall Fractional Shortening (%) | 13 ± 6 | 15 ± 3 | 6 ± 1* | 16 ± 6 | <0.001 | |
Global Circumferential Strain (%) | −14 ± 7 | −19 ± 4 | −6 ± 2* | −18 ± 2 | <0.001 | |
Global Circumferential Strain Rate (s−1) | −0.8 ± 0.3 | −1.0 ± 0.3 | −0.4 ± 0.1* | −1.0 ± 0.1 | <0.001 | |
Global Longitudinal Strain (%) | −16 ± 7 | −19 ± 4 | −8 ± 2* | −22 ± 5 | <0.001 | |
Global Longitudinal Strain Rate (s−1) | −0.8 ± 0.4 | −0.9 ± 0.2 | −0.4 ± 0.1* | −1.1 ± 0.4 | <0.001 | |
Peak-EIVPD (mm Hg) | 3.4 ± 1.7 | 4.0 ± 2.0 | 2.1 ± 0.6* | 4.0 ± 1.5 | 0.02 | |
Emax-sb1 (mm Hg/ml) | 1.6 ± 0.7 | 1.7 ± 0.5 | 2.0 ± 0.6 | 1.0 ± 0.4 | 0.02 | |
Emax-sb2 (mm Hg/ml) | 3.6 ± 1.9 | 5.3 ± 1.4 | 1.6 ± 0.6* | 3.5 ± 1.3* | 0.003 |
p < 0.05:
Dunnet comparison against the group of patients with chest pain and normal EF. Values show mean ± standard deviation. dP/dt: derivative of LV pressure with respect to time. Peak-EIVPD: peak ejection intraventricular pressure difference between the apex and the outflow tract; Emax maximal elastance. Emax-sb1 single-beat Emax estimated by method 1; Emax-sb2 Single-beat Emax estimated by method 2.