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. Author manuscript; available in PMC: 2015 Jan 1.
Published in final edited form as: Circ Cardiovasc Imaging. 2013 Oct 30;7(1):164–172. doi: 10.1161/CIRCIMAGING.113.000722

Table 2.

Hemodynamic and Echocardiographic Data

Total Chest Pain DCM Liver
cirrhosis
ANOVA
p value
n 27 10 8 9 -
Heart Rate (bpm) 72 ± 14 70 ± 10 83 ± 17 66 ± 12 -
Catheterization Data
Mean Arterial Pressure (mm Hg) 98 ± 19 102 ± 11 110 ± 20 82 ± 13* 0.001
dP/dtmax (mm Hg s−1) 1283 ± 327 1529 ± 242 957 ± 231* 1216 ± 212* <0.001
Cardiac Output (l/min) 6.9 ± 2.4 6.2 ± 1.5 5.5 ± 1.5 8.9 ± 2.7* 0.003
Cardiac Index (l/min/m2) 4.0 ± 1.2 3.9 ± 0.8 3.2 ± 0.8 4.8 ± 1.4 0.04
Right Atrial Pressure (mm Hg) 10 ± 4 8 ± 4 8 ± 5 12 ± 2* <0.001
Mean Pulmonary Pressure (mm Hg) 24 ± 6 23 ± 5 27 ± 9 21 ± 6 0.5
Pulmonary Capillary Wedge Pressure (mm Hg) 15 ± 5 13 ± 3 17 ± 6 16 ± 5 0.4
Pulmonary Vascular Resistance (dyn·cm·s−5) 120 ± 69 137 ± 49 159 ± 66 57 ± 48* 0.005
Systolic Chamber Function
Emax (mm Hg/ml) 2.8 ± 1.0 3.1 ± 0.8 2.1 ± 0.7* 3.2 ± 1.1 0.04
Preload
End-Diastolic LV Volume (ml) 114 ± 46 88 ± 24 162 ± 49* 102 ± 34 0.003
End-Diastolic LV Pressure (mm Hg) 20 ± 7 18 ± 4 21 ± 10 20 ± 7 0.9
Preload Index 0.0 ± 1.2 −0.6 ± 0.6 0.9 ± 1.4* −1.3 ± 1.1 0.03
Afterload
End-Systolic Wall Stress (mm Hg) 348 ± 117 347 ± 76 454 ± 120* 257 ± 68* <0.001
Effective Arterial Elastance (mm Hg/ml) 1.5 ± 0.7 1.6 ± 0.3 2.2 ± 0.7* 0.9 ± 0.3* <0.001
Systemic Vascular Resistance (dyn·cm·s−5) 1191 ± 589 1301 ± 400 1624 ± 659 683 ± 273* 0.001
Afterload Index 0.0 ± 1.7 0.2 ± 0.9 1.5 ± 1.7* −1.5 ± 0.7* <0.001
Chamber Remodeling
End-Systolic Volume (ml) 51 ± 38 28 ± 13 99 ± 37* 35 ± 11 <0.001
LV Mass (g) 140 ± 52 109 ± 17 184 ± 74* 134 ± 21 0.005
Noninvasive Systolic Chamber Function
Ejection Fraction (%) 54 ± 20 65 ± 7 26 ± 9* 65 ± 8 <0.001
Mid-Wall Fractional Shortening (%) 13 ± 6 15 ± 3 6 ± 1* 16 ± 6 <0.001
Global Circumferential Strain (%) −14 ± 7 −19 ± 4 −6 ± 2* −18 ± 2 <0.001
Global Circumferential Strain Rate (s−1) −0.8 ± 0.3 −1.0 ± 0.3 −0.4 ± 0.1* −1.0 ± 0.1 <0.001
Global Longitudinal Strain (%) −16 ± 7 −19 ± 4 −8 ± 2* −22 ± 5 <0.001
Global Longitudinal Strain Rate (s−1) −0.8 ± 0.4 −0.9 ± 0.2 −0.4 ± 0.1* −1.1 ± 0.4 <0.001
Peak-EIVPD (mm Hg) 3.4 ± 1.7 4.0 ± 2.0 2.1 ± 0.6* 4.0 ± 1.5 0.02
Emax-sb1 (mm Hg/ml) 1.6 ± 0.7 1.7 ± 0.5 2.0 ± 0.6 1.0 ± 0.4 0.02
Emax-sb2 (mm Hg/ml) 3.6 ± 1.9 5.3 ± 1.4 1.6 ± 0.6* 3.5 ± 1.3* 0.003
*

p < 0.05:

Dunnet comparison against the group of patients with chest pain and normal EF. Values show mean ± standard deviation. dP/dt: derivative of LV pressure with respect to time. Peak-EIVPD: peak ejection intraventricular pressure difference between the apex and the outflow tract; Emax maximal elastance. Emax-sb1 single-beat Emax estimated by method 1; Emax-sb2 Single-beat Emax estimated by method 2.