Table 2.
Genotype distributions of Apoprotein E, lipoprotein lipase and vascular endothelial growth of the Normative Aging participants between November 2000 and December 2007 in Boston, Massachusetts, USA
| Polymorphism | N (%) | |
|---|---|---|
| APOE-T530C (rs7412) | Wild | 491 (85.1) |
| Heterozygous | 83 (14.4) | |
| Homozygous | 3 (0.5) | |
| APOE-G219T (rs405509) | Wild | 162 (28.7) |
| Heterozygous | 272 (48.1) | |
| Homozygous | 131 (23.2) | |
| APOE-T392C (rs429358) | Wild | 435 (76.9) |
| Heterozygous | 120 (21.2) | |
| Homozygous | 11 (1.9) | |
| APOE-G113C (rs440446) | Wild | 220 (39.8) |
| Heterozygous | 247 (44.7) | |
| Homozygous | 86 (15.6) | |
| APOE-A491T (rs449647) | Wild | 353 (63.2) |
| Heterozygous | 182 (32.6) | |
| Homozygous | 24 (4.3) | |
| APOE-T427C (rs769446) | Wild | 486 (85.1) |
| Heterozygous | 75 (13.1) | |
| Homozygous | 10 (1.8) | |
| LPL-N291S (rs268) | Wild Type | 555 (97.2) |
| Heterozygous | 15 (2.6) | |
| Homozygous | 1 (0.2) | |
| LPL-S447X (rs328) | Wild Type | 460 (83.3) |
| Heterozygous | 86 (15.6) | |
| Homozygous | 6 (1.1) | |
| LPL-D9N (rs1801177) | Wild Type | 537 (97.8) |
| Heterozygous | 12 (2.3) | |
| Homozygous | 0 (0.0) | |
| VEGF-G634C (rs2010963) | Wild Type | 233 (42.5) |
| Heterozygous | 245 (44.7) | |
| Homozygous | 70 (12.8) | |
| APOE haplotype | E3/E3 | 358 (63.8) |
| E3/E2 | 72 (12.8) | |
| E3/E4 | 109 (19.4) | |
| Other | 22 (3.9) |
*
The sum of the subjects in each genotype may not add up to the total number of subjects due to missing genotyping data. Missing genotyping is due to a variable number of samples for each locus for which genotyping was not successful.