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. Author manuscript; available in PMC: 2014 Feb 26.
Published in final edited form as: Vaccine. 2006 Nov 29;25(11):2001–2010. doi: 10.1016/j.vaccine.2006.11.049

Fig. 8. HPV11 virion neutralization assay by quantitative RT-PCR.

Fig. 8

Authentic HPV11 virions were incubated with indicated pre-immune or immune sera at dilution 1:50 prior to infecting HaCaT cells. The ranges 69–81 and 108–120 indicate mouse (pre-)immune sera raised against synthetic L2 peptides; L1+69-81 and L1+108-120 indicate rabbit (pre-)immune sera raised against the respective chimeric proteins. H11.H3 is a neutralizing mAb raised against HPV11 virions that was used at excess concentration to ensure complete neutralization. Data are plotted as the mean + S.E. of five independent experiments as described in materials and methods. Pre-immune and immune sera were compared within groups using Student’s t-test, and p-values ≤ 0.05 (indicated by stars) are considered significant.