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Human immunodeficiency virus type 1 (HIV-1) RNA–producing lymph node cells predicted plasma viral load, after adjusting for sex, race, age, and peripheral blood CD4+ T-cell count (P < .001). After adjusting for race, age, CD4+ T-cell count, and HIV-1 RNA–producing cells, women still had a significantly lower viral load than men (P = .018). Viral load did not significantly differ between blacks and all other races (P = .46). The slope did not differ by sex (P = .16).
