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Baytril treatment reduced the Bordetella pertussis median infectious dose (ID50). Wild-type C57BL/6 mice were either treated 3 times with Baytril (light) or left untreated (dark). All mice were then inoculated with indicated doses of B. pertussis strain 536 in 10 µL, and levels of B. pertussis nasal cavity colonization were assessed 3 days after inoculation. Error bars represent SDs. Abbreviations: CFU, colony-forming units; ND, not detected.
