FIG. 4.
Age-related changes of protein expression levels in SGNs. DAB staining (A, B, C, D, E,F) of serial sections from the cochlear middle turn. (A, B) GABAARα1 protein expression decreased with age. (C, D) nAChRβ2 protein expression declined with age. (E, F) NMDARNR1 protein expression increased with age. (G, H, I,) GABAARα1, nAChRβ2 and NMDARNR1 protein expression in basal, middle and apical turns in young adult and old age mice. Bar indicate means ± s.d. for young adult (2–3 month) and old mice (24–32 month). *p<0.5, **p<0.01. Arrow: labeled SGNs. Scale Bar: 25 μm.