| goral(t) |
Oral dose (mol) bioavailable per unit of time which can describe time varying inputs |
| gdermal(t) |
Dermal dose (mol) bioavailable per unit of time which can describe time varying inputs |
| ginh(t) |
Inhalation dose (mol) bioavailable per unit of time which can describe time varying inputs |
| D(t) |
Amounts of cis- and trans-permethrin or cypermethrin (mol) bioavailable at skin surface as a function of time |
| GI(t) |
Amounts of cis- and trans-permethrin or cypermethrin (mol) bioavailable in the gastrointestinal tract as a function of time |
| R(t) |
Amounts of cis- and trans-permethrin or cypermethrin (mol) bioavailable in the respiratory tract as a function of time |
| Bcis(t) |
Burden of cis-permethrin or cypermethrin (mol) in blood and tissues in dynamical equilibrium with blood as a function of time |
| Btrans(t) |
Burden of trans-permethrin or cypermethrin (mol) in blood and tissues in dynamical equilibrium with blood as a function of time |
| Scis(t) |
Burden of cis-permethrin or cypermethrin (mol) in storage tissues (mol) as a function of time |
| Strans(t) |
Burden of trans-permethrin or cypermethrin (mol) in storage tissues (mol) as a function of time |
| Mcis-DCCA(t) |
Body burden of cis-DCCA (mol) as a function of time |
| Mtrans-DCCA(t) |
Body burden of trans-DCCA (mol) as a function of time |
| M3PBA(t) |
Body burden of 3-PBA (mol) as a function of time |
| Mnot observed(t) |
Body burden of non-monitored metabolites (mol) as a function of time |
| Ucis-DCCA(t) |
Cumulative amounts of cis-DCCA in urine (mol) as a function of time |
| Utrans-DCCA(t) |
Cumulative amounts of trans-DCCA in urine (mol) as a function of time |
| U3PBA(t) |
Cumulative amounts of 3-PBA in urine (mol) as a function of time |
| QUcis-DCCA(t) |
Urinary excretion rate of cis-DCCA in urine (mol) as a function of time = Mcis-DCCA(t)×kMU_cis
|
| QUtrans-DCCA(t) |
Urinary excretion rate of trans-DCCA in urine (mol) as a function of time = Mtrans-DCCA(t)×kMU_trans
|
| QU3PBA(t) |
Urinary excretion rate of 3-PBA in urine (mol) as a function of time = M3PBA(t)×kMU_3PBA
|
| Fcis-DCCA(t) |
Cumulative amounts of cis-DCCA in feces (mol) as a function of time |
| Ftrans-DCCA(t) |
Cumulative amounts of trans-DCCA in feces (mol) as a function of time |
| F3PBA(t) |
Cumulative amounts of 3-PBA in feces (mol) as a function of time |
| fabs_oral_cis
|
Oral absorption fraction of cis-permethrin or cypermethrin |
| fabs_oral_trans
|
Oral absorption fraction of trans-permethrin or cypermethrin |
| fabs_dermal_cis
|
Dermal absorption fraction of cis-permethrin or cypermethrin |
| fabs_dermal_trans
|
Dermal absorption fraction of trans-permethrin or cypermethrin |
| kabs_oral_cis
|
Oral absorption rate of cis-permethrin or cypermethrin (h−1) |
| kabs_oral_trans
|
Oral absorption rate of trans-permethrin or cypermethrin (h−1) |
| kabs_dermal_cis
|
Dermal absorption rate of cis-permethrin or cypermethrin (h−1) |
| kabs_dermal_trans
|
Dermal absorption rate of trans-permethrin or cypermethrin (h−1) |
| kabs_inh_cis
|
Respiratory absorption rate of cis-permethrin or cypermethrin (h−1) |
| kabs_inh_trans
|
Respiratory absorption rate of trans-permethrin or cypermethrin (h−1) |
| kBS_cis
|
Blood to storage tissues transfer rate of cis-permethrin (h−1) |
| kBS_trans
|
Blood to storage tissues transfer rate of trans-permethrin (h−1) |
| kSB_cis
|
Storage tissues to blood transfer rate of cis-permethrin (h−1) |
| kSB_trans
|
Storage tissues to blood transfer rate of trans-permethrin (h−1) |
| kBM_cis
|
Biotransformation rate of cis-permethrin or cypermethrin into cis-DCCA (h−1) |
| kBM_trans
|
Biotransformation rate of trans-permethrin or cypermethrin into trans-DCCA (h−1) |
| kBM_3PBA_cis
|
Biotransformation rate of cis- permethrin or cypermethrin into 3-PBA (h−1) |
| kBM_3PBA_trans
|
Biotransformation rate of trans- permethrin or cypermethrin into 3-PBA (h−1) |
| kBM_NO_cis
|
Biotransformation rate of cis-permethrin or cypermethrin into non-observed cis-derivative metabolites (h−1) |
| kBM_NO_trans
|
Biotransformation rate of trans-permethrin or cypermethrin into non-observed trans-derivative metabolites (h−1) |
| kBM_NO_3PBA_cis
|
|
|
Biotransformation rate of cis-permethrin or cypermethrin into non-observed cis-phenoxy derivatives (h−1) |
| kBM_NO_3PBA_trans
|
Biotransformation rate of trans-permethrin or cypermethrin into non-observed trans-phenoxy derivatives (h−1) |
| kMU_cis
|
Transfer rate of cis-DCCA from the body to urine (h−1) |
| kMU_trans
|
Transfer rate of trans-DCCA from the body to urine (h−1) |
| kMU_3PBA
|
Transfer rate of 3-PBA from the body to urine (h−1) |
| kMF_cis
|
Transfer rate of cis-DCCA from the body to feces (h−1) |
| kMF_trans
|
Transfer rate of trans-DCCA from the body to feces (h−1) |
| kMF_3PBA
|
Transfer rate of 3-PBA from the body to feces (h−1) |
| kmetabolism_cis
|
Biotransformation rate of cis-permethrin or cypermethrin into cis-metabolite forms or 3-PBA ( = kBM_cis+kBM_NO_cis) (h−1) |
| kmetabolism_trans
|
|
|
Biotransformation rate of trans-permethrin or cypermethrin into trans-metabolite forms or 3-PBA ( = kBM_trans+kBM_NO_trans) (h−1) |
| kelim_cis
|
Total excretion rate of cis-DCCA = (kMU_cis+kMF_cis) (h−1) |
| kelim_trans
|
Total excretion rate of trans-DCCA = (kMU_trans+kMF_trans) (h−1) |
| kelim_3PBA
|
Total excretion rate of 3-PBA = (kMU_3PBA+kMF_3PBA) (h−1) |
| ωcis
|
kBM_cis×kMU_cis
|
| ωtrans
|
kBM_trans×kMU_trans
|
| ω3PBA
|
kBM_3PBA×kMU_3PBA
|
