. 2014 Feb 26;9(2):e89094. doi: 10.1371/journal.pone.0089094

Table 1. Mutation detection efficiency using INNOLiPA tests: CFTR19 and CFTR17TnUpdate.

Mutations detected in a patient	Number of CF patients	Alleles with no mutation identified	Alleles with CF mutations detected using INNOLiPA tests		Further molecular analysis
			CFTR_19	CFTR_17TnUpdate^a
both	503 (68.1%)	0	888 (60.2%)	118 (8.0%)	Not necessary
one	109 (14.8%)	109	98 (6.6%)	11 (0.7%)	Yes
none	126 (17.1%)	252	0	0	Yes

Legend: ^a I148T included in CFTR-17TnUpdate was not counted as a mutation if not in cis with c.3067-72del6 (l.n. 3199del6); c.1210(-12)T_n site in intron 9 (l.n.IVS8-T_n) without data on the associated TG repeat was not counted as a mutation.