Table 1. Case studies from the human study collection.
Type | Case study | Results | Details |
Absolute expression | Stem cells | Query | microRNA and mRNA expression profiles of human pancreatic islet-like cell clusters (E-GEOD-14503) |
Result #1 | Human embryonic stem cells derived from embryos at different stages of development share similar transcription profiles (E-GEOD-29625) | ||
Result #2 | microRNA and mRNA expression profiles of human embryonic stem cells treated with activin A (E-GEOD-16910) | ||
Result #3 | Transcription profiling by array of human embryonic and induced pluripotent stem cells (E-GEOD-23402) | ||
Top genes | Cathepsin L2 (CTSL2), von Willebrand factor D and EGF domains (VWDE), ZFP42 zinc finger protein (ZFP42) | ||
Muscle tissue | Query | Gene expression profiles in muscle tissue from FSHD patients (E-GEOD-15090) | |
Result #1 | A transcriptional map of the impact of endurance exercise training on skeletal muscle phenotype (resting muscle after endurance training) (E-GEOD-35659) | ||
Result #2 | Expression data of normal human extraocular muscle and strabismic human extraocular muscle (E-GEOD-38780) | ||
Result #3 | Gene expression in skeletal muscle of cancer patients before and after potentially curative surgery (E-GEOD-34111) | ||
Top genes | Mindbomb E3 ubiquitin protein ligase 1 (MIB1), bestrophin 3 (BEST3), myosin light chain kinase family, member 4 (MYLK4) | ||
Differential expression | Hepatocytes | Query | Transcription Profiling of human primary hepatocytes after treatment with pirinixic acid (E-GEOD-17251) |
Result #1 | HepaRG cells as a model of the primary human hepatocyte transcriptome (E-GEOD-18269) | ||
Result #2 | Atorvastatin, rosuvastatin and rifampicin effect on human primary hepatocyte transcriptome (E-GEOD-24187) | ||
Result #3 | Transcriptome Analysis Identifies Fn14, a TNF Superfamily Receptor Member, as a Therapeutic Target in Alcoholic Hepatitis (E-GEOD-28619) | ||
Top genes | WD repeat-containing protein 72 (WDR72), indoleamine 2,3-dioxygenase 2 (IDO2), Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3) | ||
Prostate cancer | Query | Identification of an SRF- and androgen-dependent gene signature in prostate cancer (E-GEOD-22606) | |
Result #1 | Expression data from androgen treated LNCaP cells (E-GEOD-17044) | ||
Result #2 | Atorvastatin, rosuvastatin and rifampicin effect on human primary hepatocyte transcriptome [Affymetrix platform] (E-GEOD-24187) | ||
Result #3 | Expression data from breast cancer cell lines with various colony-forming ability (E-GEOD-15026) | ||
Top genes | Vacuolar protein sorting 13 homolog B (VPS13B), histidine triad nucleotide binding protein 1 (HINT1), diacylglycerol kinase, eta (DGKH) |
ArrayExpress study identifiers are shown next to each study title. The “Type” column indicates if a case study corresponds to absolute or differential expression data. The “Results” column displays for every case study (1) the query study, (2) the top-three most relevant studies, and (3) the three protein-coding genes with the highest IDF score that are active in the query and the top-three most relevant studies.