Skip to main content
. 2014 Feb 26;9(2):e89573. doi: 10.1371/journal.pone.0089573

Table 1. Pre- and post-treatment renal outcomes in 171 HIV-infected patients on ART followed up after a median of 2 years at Bugando Medical Centre.

Characteristic Value At ART Initiation [Number(percent) or Median (IQR)] Value At Follow-up [Number(percent) or Median (IQR)] p-value
eGFR by CG equation (mL/min/1.73 m2) 74.1 (55.8–100.1) 103.4 (85.3–135.6) <0.001
eGFR by MDRD equation (mL/min/1.73 m2) 87.5 (64.3–125.3) 125.1 (103.5–152.8) <0.001
CKD Stage by CG equation
Stage 0 (eGFR >90) 40 (23.4) 121 (70.8) <0.001
Stage 1 (eGFR <90 with proteinuria) 24 (14.0) 14 (8.2)
Stage 2 (eGFR 60–89) 71 (41.5) 34 (19.9)
Stage 3 (eGFR 30–59) 36 (21.1) 2 (1.2)
Stage 4 (eGFR 15–29) 0 0
Stage 5 (eGFR <15) 0 0
CKD Stage by MDRD equation
Stage 0 (eGFR >90) 55 (32.2) 133 (77.8) <0.001
Stage 1 (eGFR <90 with proteinuria) 28 (16.4) 15 (8.8)
Stage 2 (eGFR 60–89) 57 (33.3) 21 (12.3)
Stage 3 (eGFR 30–59) 31 (18.1) 2 (1.2)
Stage 4 (eGFR 15–29) 0 0
Stage 5 (eGFR <15) 0 0
Serum creatinine (µmol/L) 81.0 (62.8–105.3) 60.9 (50.0–71.4) <0.001
Microalbuminuria (>20 mg/dL) 123 (71.9%) 74 (43.5%) <0.001
Proteinuria 61 (35.7%) 15 (8.8%) <0.001

Non-missing data are included in each calculation.