Table 1. Pre- and post-treatment renal outcomes in 171 HIV-infected patients on ART followed up after a median of 2 years at Bugando Medical Centre.
Characteristic | Value At ART Initiation [Number(percent) or Median (IQR)] | Value At Follow-up [Number(percent) or Median (IQR)] | p-value |
eGFR by CG equation (mL/min/1.73 m2) | 74.1 (55.8–100.1) | 103.4 (85.3–135.6) | <0.001 |
eGFR by MDRD equation (mL/min/1.73 m2) | 87.5 (64.3–125.3) | 125.1 (103.5–152.8) | <0.001 |
CKD Stage by CG equation | |||
Stage 0 (eGFR >90) | 40 (23.4) | 121 (70.8) | <0.001 |
Stage 1 (eGFR <90 with proteinuria) | 24 (14.0) | 14 (8.2) | |
Stage 2 (eGFR 60–89) | 71 (41.5) | 34 (19.9) | |
Stage 3 (eGFR 30–59) | 36 (21.1) | 2 (1.2) | |
Stage 4 (eGFR 15–29) | 0 | 0 | |
Stage 5 (eGFR <15) | 0 | 0 | |
CKD Stage by MDRD equation | |||
Stage 0 (eGFR >90) | 55 (32.2) | 133 (77.8) | <0.001 |
Stage 1 (eGFR <90 with proteinuria) | 28 (16.4) | 15 (8.8) | |
Stage 2 (eGFR 60–89) | 57 (33.3) | 21 (12.3) | |
Stage 3 (eGFR 30–59) | 31 (18.1) | 2 (1.2) | |
Stage 4 (eGFR 15–29) | 0 | 0 | |
Stage 5 (eGFR <15) | 0 | 0 | |
Serum creatinine (µmol/L) | 81.0 (62.8–105.3) | 60.9 (50.0–71.4) | <0.001 |
Microalbuminuria (>20 mg/dL) | 123 (71.9%) | 74 (43.5%) | <0.001 |
Proteinuria | 61 (35.7%) | 15 (8.8%) | <0.001 |
Non-missing data are included in each calculation.