Table 2. Univariable and Multivariable Analyses of Baseline Predictors of Decreased Renal Function (eGFR <90 mL/min/1.73 m2) after a Median of 2 years of Antiretroviral Therapy (n = 171).
| Univariable Multivariable | ||||||
| Variable | Number (%) ormedian (IQR)with eGFR<90(n = 36) | Number (%) ormedian (IQR) witheGFR>90 (n = 135) | OR [95% CI] | P value | OR [95% CI] | P value |
| Age at ART initiation (yrs) | 43 (38–48) | 38 (33–43) | 1.06 [1.02–1.1] | 0.004 | 1.06 [1.01–1.11] | 0.009 |
| Female sex | 23 (63.9) | 98 (72.6) | 1.5 [0.7–3.3] | 0.31 | ||
| Education | ||||||
| Uneducated | 10 (27.8) | 27 (20.0) | 0.86 [0.5–1.5] | 0.59 | ||
| Primary | 21 (58.3) | 92 (68.2) | ||||
| Secondary | 4 (11.1) | 11 (8.2) | ||||
| College | 1 (2.8) | 5 (3.7) | ||||
| Unemployed or petty trader | 28 (77.8) | 109 (80.7) | 0.83 [0.3–2.0] | 0.69 | ||
| Living alone | 17 (47.2) | 58 (43.0) | 1.2 [0.6–2.5] | 0.64 | ||
| Baseline CD4 (cells/µl) | 115 (62–174) | 159 (85–203) | 0.995 [0.99–0.999] | 0.030 | 0.99 [0.989–0.999] | 0.015 |
| Baseline BMI (kg/m2) | 21 (19–22.5) | 21 (19–24) | 0.9 [0.8–0.99] | 0.036 | 0.88 [0.78–0.998] | 0.047 |
| Baseline serum creatinine(umol/l) | 72 (59–104) | 82(64–105) | 0.99 [0.98–1.01] | 0.30 | ||
| Baseline eGFR (ml/min/1.73 m2) | 87.9 (62.6–115.5) | 80.6 (63.5–105.1) | 1.0 [0.99–1.01] | 0.75 | ||
| Received tenofovir-basedbaseline ART regimen | 6 (16.7) | 34 (25.2) | 0.59 [0.2–1.5] | 0.29 | ||