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. 2014 Feb 26;9(2):e89547. doi: 10.1371/journal.pone.0089547

Figure 4. Effect of 8 h overnight fast on muscle and plasma amino acid (leucine, glutamine) concentrations in MS-Slc7a5-KO mice.

Figure 4

Mean ± SEM for n = 6–9 (WT) and 3–5 (MS-Slc7a5-KO) mice. (A) Intramuscular AA are significantly lower after 8 h fast in WT animals but not MS-Slc7a5-KO animals. *and ***indicate p<0.05 and p<0.001 respectively by Bonferroni’s post t-test). (B) Plasma glutamine concentrations are significantly lower after 8 h fast for both genotypes (***indicates p<0.001 by Bonferroni’s post t-test), although an overall effect of fasting on plasma leucine is detected (F (1, 19) = 5.49, p = .030), the difference does not achieve p<0.05 for either genotype.