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. 2014 Feb 26;9(2):e89970. doi: 10.1371/journal.pone.0089970

Figure 3. KEGG pathway analysis suggests similar patterns of expression.

Figure 3

The Kyoto Encyclopedia of Gene and Genomes (KEGG) pathway analysis resulted in similar lists of modulated pathways representing proteins found to be significantly within the different cohorts (p<0.05; t-test). Venn diagrams show divergences in the proteins that make up those pathways. Both WT and Tg-SwDI animals show changes in (A) metabolic pathways, specifically (B) oxidative phosphorylation, though only a third of the modulated proteins represented by the KEGG pathways are shared. The (C) gap junction pathway share many more proteins between WT and Tg-SwDI cohorts.