. Author manuscript; available in PMC: 2015 Jan 17.

Published in final edited form as: Oncogene. 2013 Aug 26;33(29):3861–3868. doi: 10.1038/onc.2013.350

Table 1.

Loss of Kcnq1 enhances tumor multiplicity in Apc^Min mice.

Males	N	colon	Proximal SI	Distal SI
Kcnq1 ^+/+	30	1.8 ± 1.7	11 ± 8	56 ± 41
Kcnq1 ^+/−	34	^*3.8 ± 2.3	^*18 ± 13	^*76 ± 38
Kcnq1 ^−/−	10	2.6 ± 2.8	^*36 ± 16	52 ± 43
Females
Kcnq1 ^+/+	26	1.2 ± 1.7	14 ± 9	^*58 ± 25
Kcnq1 ^+/−	46	^*2.5 ± 2.2	20 ± 12	^*84 ± 37
Kcnq1 ^−/−	13	2.1 ± 2.0	^*22 ± 11	30 ± 16

Apc^Min Kcnq1^+/+, Apc^Min Kcnq1^+/− and Apc^MinKcnq1^−/− mice were sacrificed at 120 days of age and tumors counted and measured.

P values: < 0.05; Two-sided P values for tumor counts were determined by use of the Wilcoxon Rank Sum Test comparing gender and age-matched classes produced in the same genetic crosses.