Table 1.
Lung cancer incidence by trial arm and major covariates
| Arm | Total Enrolled | # Incident Lung Cancers |
Incidence Rate (per 100,000 PY) |
Incidence RR (95% CI) 1 |
|
|---|---|---|---|---|---|
| Subset | N | ||||
| All | LDCT | 26722 | 1089 | 662 | - |
| All | CXR | 26730 | 969 | 588 | - |
| N(% within arm) | |||||
| Women | LDCT | 10953 (41) | 434 | 638 | Referent |
| Men | LDCT | 15769 (59) | 655 | 678 | 1.06 (0.94–1.20) |
| Women | CXR | 10969 (41) | 395 | 580 | Referent |
| Men | CXR | 15761 (59) | 574 | 594 | 1.02 (0.90–1.16) |
| Age < 65 | LDCT | 19612 (73) | 620 | 508 | Referent |
| Age ≥ 65 | LDCT | 7110 (27) | 469 | 1100 | 2.16 (1.92–2.44) |
| Age < 65 | CXR | 19622 (73) | 549 | 450 | Referent |
| Age ≥ 65 | CXR | 7108 (27) | 420 | 981 | 2.18 (1.93–2.49) |
| Former Smoker | LDCT | 13862 (52) | 452 | 522 | Referent |
| Current Smoker | LDCT | 12860 (48) | 637 | 816 | 1.56 (1.39–1.76) |
| Former Smoker | CXR | 13830 (52) | 365 | 421 | Referent |
| Current Smoker | CXR | 12900 (48) | 604 | 773 | 1.84 (1.62–2.09) |
1
. Risk Ratio across covariate categories within trial arm (e.g., for men versus women within the LDCT arm).