. Author manuscript; available in PMC: 2014 Apr 1.

Published in final edited form as: Mol Imaging Biol. 2013 Apr;15(2):230–237. doi: 10.1007/s11307-012-0583-x

Table 2.

Relationship between PET and biopsy data. Biopsy site, contralateral, and average SUVR values, with cerebellum and pons as the reference regions, correlated with the percent of biopsy specimen staining for amyloid β based on 4 G8. SUVR-PONS standard uptake value ratio using pons as the reference region

Standard of truth (SOT)
SUVR-CER from PET imaging
IHC 4 G8	Biopsy site		Contralateral to biopsy site		Average region
	% area of amyloid		% area of amyloid		% area of amyloid
	p value	R²	p value	R²	p value	R²
	0.0174	0.64	0.0107	0.69	0.0025	0.81
	Pearson correlation coefficient		Pearson correlation coefficient		Pearson correlation coefficient
	Parameter estimate	p value	Parameter estimate	p value	Parameter estimate	p value
	0.799	0.0174	0.831	0.0107	0.898	0.0025
SUVR-PONS from PET imaging
IHC 4 G8	Biopsy site		Contralateral to biopsy site		Composite region
	% area of amyloid		% area of amyloid		% area of amyloid
	p value	R²	p value	R²	p value	R²
	0.0244	0.60	0.0190	0.63	0.0051	0.76
	Pearson correlation coefficient		Pearson correlation coefficient		Pearson correlation coefficient
	Parameter estimate	p value	Parameter estimate	p value	Parameter estimate	p value
	0.773	0.0244	0.793	0.0190	0.869	0.0051