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Bmp6-/- mice have reduced trabecular bone volume (BV). (a) μCT analyses of WT and Bmp6-/- embryos at days 15 (E15), 17 (E17) and at 2 days of postnatal (p.n.) life. (b) μCT of distal femurs. (c) Real time PCR expression of Bmp2 and -7 in the femur of WT and Bmp6-/- mice. BV/TV bone volume/tissue volume; significant difference from WT (P < 0.05, ANOVA Dunnett test) (*)
