Table 4.
Hematological values of the silkworm extract powder in male rats
| Parameter | Main group (mg/kg/day) | Recovery group (mg/kg/day) | |||||
|---|---|---|---|---|---|---|---|
|
|
|
||||||
| 0 | 500 | 1000 | 2000 | 0 | 2000 | ||
|
| |||||||
| RBC | (106/μl) | 8.91 ± 0.43 | 8.68 ± 0.23 | 8.67 ± 0.22 | 8.91 ± 0.32 | 8.87 ± 0.32 | 8.75 ± 0.34 |
| HGB | (g/dl) | 16.1 ± 0.7 | 15.9 ± 0.4 | 15.9 ± 0.3 | 16.1 ± 0.6 | 16.5 ± 0.5 | 16.5 ± 0.3 |
| HCT | (%) | 46.5 ± 1.7 | 46.3 ± 1.2 | 46.1 ± 1.0 | 47.0 ± 1.8 | 45.6 ± 1.4 | 46.0 ± 1.2 |
| MCV | (fl) | 52.3 ± 1.5 | 53.3 ± 0.8 | 53.2 ± 0.8 | 52.8 ± 1.1 | 51.5 ± 0.8 | 52.6 ± 1.3 |
| MCH | (pg) | 18.1 ± 0.6 | 18.4 ± 0.4 | 18.4 ± 0.3 | 18.0 ± 0.4 | 18.6 ± 0.6 | 18.9 ± 0.5 |
| MCHC | (g/dl) | 34.5 ± 0.4 | 34.4 ± 0.5 | 34.6 ± 0.2 | 34.2 ± 0.5 | 36.2 ± 0.6 | 35.9 ± 0.4 |
| RDW | (%) | 12.7 ± 0.3 | 12.8 ± 0.3 | 12.5 ± 0.2* | 12.5 ± 0.2 | 12.8 ± 0.1 | 12.6 ± 0.3 |
| HDW | (g/dl) | 2.73 ± 0.14 | 2.70 ± 0.09 | 2.67 ± 0.12 | 2.60 ± 0.10 | 2.78 ± 0.11 | 2.73 ± 0.16 |
| RET | (%) | 2.56 ± 0.24 | 2.69 ± 0.28 | 2.55 ± 0.22 | 2.60 ± 0.12 | 2.46 ± 0.32 | 2.50 ± 0.19 |
| PLT | (103/μl) | 935.4 ± 80.4 | 948.4 ± 90.6 | 882.1 ± 195.1 | 966.7 ± 88.1 | 922.8 ± 70.4 | 954.0 ± 93.1 |
| MPV | (fl) | 4.8 ± 0.2 | 4.9 ± 0.3 | 5.0 ± 0.5 | 5.0 ± 0.3 | 5.7 ± 0.1 | 5.6 ± 0.4 |
| WBC | (103/μl) | 8.59 ± 1.50 | 9.98 ± 2.24 | 8.71 ± 1.34 | 9.95 ± 1.69 | 8.98 ± 1.64 | 8.46 ± 1.67 |
| NEU | (%) | 23.9 ± 9.6 | 23.8 ± 6.2 | 19.1 ± 6.6 | 23.0 ± 10.0 | 19.7 ± 7.0 | 19.1 ± 4.7 |
| LYM | (%) | 69.5 ± 9.6 | 70.2 ± 6.7 | 73.8 ± 7.5 | 70.1 ± 10.4 | 73.7 ± 6.3 | 74.6 ± 4.7 |
| MONO | (%) | 4.2 ± 1.4 | 3.8 ± 0.7 | 4.4 ± 0.9 | 4.4 ± 0.9 | 4.3 ± 1.7 | 3.9 ± 0.8 |
| EOS | (%) | 1.3 ± 0.1 | 1.2 ± 0.3 | 1.7 ± 0.4 | 1.4 ± 0.2 | 1.4 ± 0.3 | 1.4 ± 0.2 |
| BASO | (%) | 0.5 ± 0.1 | 0.5 ± 0.1 | 0.5 ± 0.2 | 0.5 ± 0.1 | 0.2 ± 0.1 | 0.2 ± 0.1 |
| LUC | (%) | 0.6 ± 0.3 | 0.5 ± 0.2 | 0.6 ± 0.2 | 0.6 ± 0.2 | 0.7 ± 0.3 | 0.8 ± 0.2 |
| PT | (sec) | 8.63 ± 0.48 | 8.73 ± 0.50 | 8.94 ± 0.61 | 8.67 ± 0.43 | 9.09 ± 0.17 | 9.00 ± 0.28 |
| APTT | (sec) | 19.3 ± 0.6 | 19.0 ± 1.0 | 18.5 ± 2.6 | 18.9 ± 1.5 | 20.2 ± 0.4 | 19.7 ± 1.3 |
| No. of animals | 10 | 10 | 10 | 10 | 5 | 5 | |
RBC: red blood cell count, HGB: hemoglobin, HCT: hematocrit, MCV: mean corpuscular volume, MCH: mean corpuscular hemoglobin, MCHC: mean corpuscular hemoglobin concentration, RDW: red cell distribution width, HDW: hemoglobin distribution width, RET: reticulocyte, PLT: platelet, MPV: mean platelet volume, WBC: white blood cell count, NEU: neutrophils, LYM: lymphocytes, MONO: monocytes, EOS: eosinophils, BOS: basophils, LUC: large unstained cells, PT: prothrombin time, APTT: active partial thromboplastin time.
Values are mean ± S.D.
**: Significantly different from control at p < 0.01.