Table 6.
Serum biochemical values of the silkworm extract powder in male rats
| Parameter | Main group (mg/kg/day) | Recovery group (mg/kg/day) | |||||
|---|---|---|---|---|---|---|---|
|
|
|
||||||
| 0 | 500 | 1000 | 2000 | 0 | 2000 | ||
|
| |||||||
| AST | (U/L) | 83.4 ± 15.1 | 75.3 ± 9.0 | 86.2 ± 13.2 | 79.5 ± 8.0 | 106.6 ± 28.3 | 94.2 ± 9.1 |
| ALT | (U/L) | 41.0 ± 5.8 | 36.8 ± 5.7 | 42.6 ± 5.1 | 41.0 ± 5.0 | 52.7 ± 14.6 | 44.0 ± 5.4 |
| ALP | (U/L) | 101.6 ± 20.0 | 89.1 ± 16.4 | 100.3 ± 25.0 | 108.0 ± 19.6 | 97.8 ± 27.8 | 90.1 ± 18.2 |
| CPK | (U/L) | 172.5 ± 83.1 | 164.0 ± 76.1 | 166.3 ± 91.1 | 139.0 ± 71.8 | 210.8 ± 48.9 | 319.0 ± 48.5** |
| TBil | (mg/dl) | 0.15 ± 0.02 | 0.15 ± 0.01 | 0.15 ± 0.02 | 0.15 ± 0.01 | 0.19 ± 0.08 | 0.16 ± 0.01 |
| GLU | (mg/dl) | 117.7 ± 7.8 | 126.5 ± 11.1 | 126.4 ± 10.1 | 126.7 ± 7.0 | 112.3 ± 9.3 | 120.4 ± 7.3 |
| TCho | (mg/dl) | 110.9 ± 13.6 | 106.4 ± 14.8 | 92.8 ± 15.5* | 100.9 ± 11.7 | 111.2 ± 12.9 | 111.4 ± 10.9 |
| TG | (mg/dl) | 40.3 ± 11.1 | 51.7 ± 24.7 | 42.7 ± 12.3 | 41.1 ± 5.7 | 52.2 ± 10.1 | 59.2 ± 9.8 |
| TP | (g/dl) | 6.13 ± 0.20 | 6.12 ± 0.15 | 5.94 ± 0.19 | 6.03 ± 0.27 | 6.03 ± 0.23 | 5.94 ± 0.19 |
| ALB | (g/dl) | 2.94 ± 0.12 | 2.94 ± 0.07 | 2.91 ± 0.12 | 2.94 ± 0.09 | 2.88 ± 0.11 | 2.90 ± 0.10 |
| A/G | (ratio) | 0.92 ± 0.04 | 0.92 ± 0.04 | 0.96 ± 0.05 | 0.95 ± 0.07 | 0.92 ± 0.02 | 0.95 ± 0.05 |
| BUN | (mg/dl) | 15.8 ± 1.3 | 14.6 ± 1.3 | 14.8 ± 2.2 | 16.1 ± 1.5 | 15.5 ± 2.7 | 15.9 ± 1.8 |
| CRE | (mg/dl) | 0.47 ± 0.03 | 0.48 ± 0.03 | 0.47 ± 0.03 | 0.47 ± 0.03 | 0.52 ± 0.05 | 0.50 ± 0.03 |
| IP | (mg/dl) | 6.35 ± 0.21 | 6.28 ± 0.19 | 6.18 ± 0.31 | 6.46 ± 0.33 | 5.96 ± 0.65 | 5.97 ± 0.31 |
| Ca2+ | (mg/dl) | 9.73 ± 0.22 | 9.82 ± 0.20 | 9.61 ± 0.15 | 9.74 ± 0.27 | 9.59 ± 0.27 | 9.61 ± 0.15 |
| Na+ | (mmol/L) | 139.78 ± 1.01 | 139.44 ± 0.71 | 139.63 ± 1.08 | 139.35 ± 0.63 | 139.79 ± 0.84 | 139.15 ± 0.93 |
| K+ | (mmol/L) | 4.74 ± 0.18 | 4.82 ± 0.18 | 4.65 ± 0.26 | 4.84 ± 0.15 | 4.57 ± 0.19 | 4.88 ± 0.13* |
| Cl- | (mmol/L) | 102.43 ± 1.03 | 101.70 ± 0.73 | 102.28 ± 1.23 | 101.67 ± 1.30 | 101.30 ± 0.61 | 101.73 ± 0.43 |
| No. of animals | 10 | 10 | 10 | 10 | 5 | 5 | |
AST; aspartate aminotransferase, ALT; alanine aminotransferase, ALP; alkaline phosphatase, CPK; creatine phosphokinase, TBil; total bilirubin, GLU: glucose, TCho; total cholesterol, TG: triglyceride, TP; total protein, ALB: albumin, A/G; albumin/globulin, BUN; blood urea nitrogen, CRE: creatinine, IP: inorganic phosphorus. Ca2 : calcium, Na : sodium, K : potassium, Cl−: chloride. Values are mean ± S.D.
*/** Significantly different from control at p<0.05/p<0.01.