Table 3. Meta-analysis of the AGT M235T polymorphism on HF risk.
| TT vs. MM | MT vs. MM | MT/TT vs. MM (dominant) | TT vs. MM/MT (recessive) | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Variable | na | OR (95% CI) | Pb | OR (95% CI) | Pb | OR (95% CI) | Pb | OR (95% CI) | Pb |
| Total | 7 | 1.17 (0.62–2.19)c | 0.012 | 0.97 (0.77–1.22) | 0.087 | 1.07 (0.67–1.69)c | 0.035 | 1.23 (0.86–1.76)c | 0.002 |
| Ethnicities | |||||||||
| Asian | 3 | 0.62 (0.27–1.45) | 0.467 | 0.39 (0.17–0.92) | 0.873 | 0.54 (0.24–1.22) | 0.543 | 1.39 (0.83–2.33) | 0.044 |
| European | 3 | 1.66 (0.70–3.92)c | 0.004 | 1.05 (0.82–1.33) | 0.086 | 1.31 (0.76–2.28)c | 0.014 | 1.40 (0.77–2.58) | 0.026 |
aNumber of comparisons.
bP value of Q-test for heterogeneity test.
cRandom-effects model was used when P value for heterogeneity test <0.05; otherwise, fix-effects model was used.