Table 2.
Office probing outcomes according to baseline characteristicsa
| Baseline characteristics | N eyes | Eyes with success N (%)b | Adjusted relative risk for success and 95% CIc |
|---|---|---|---|
| Total | 360 | 262 (73) | — |
| Age at surgery, monthsd | |||
| 6 to <7 | 57 | 44 (77) | — |
| 7 to <8 | 65 | 53 (82) | 1.04 (0.85–1.28) |
| 8 to <9 | 60 | 40 (67) | 0.93 (0.72–1.18) |
| 9 to <10 | 68 | 50 (74) | 1.02 (0.83–1.26) |
| 10 to <11 | 46 | 30 (65) | 0.87 (0.64–1.16) |
| 11 to <12 | 26 | 18 (69) | 0.93 (0.67–1.30) |
| 12 to <15 | 38 | 27 (71) | 0.99 (0.75–1.31) |
| Sex | |||
| Female | 171 | 124 (73) | 0.95 (0.84–1.07) |
| Male | 189 | 138 (73) | — |
| Race/ethnicity | |||
| White | 278 | 209 (75) | — |
| Hispanic/Latino | 42 | 29 (69) | 0.96 (0.79–1.17) |
| Other | 36 | 23 (64) | 0.87 (0.66–1.16) |
| Laterality | |||
| Unilateral | 208 | 166 (80) | — |
| Bilateral | 152 | 96 (63) | 0.78 (0.66–0.92) |
| Epiphora | |||
| Present | 273 | 196 (72) | 1.07 (0.89–1.30) |
| Absent | 87 | 66 (76) | — |
| Mucous discharge | |||
| Present | 254 | 182 (72) | 0.92 (0.75–1.13) |
| Absent | 106 | 80 (75) | — |
| Increased tear film | |||
| Present | 354 | 257 (73) | 1.03 (0.72–1.48) |
| Absent | 6 | 5 (83) | — |
| Number of clinical signse | |||
| 1 | 46 | 38 (83) | — |
| 2 or 3 | 314 | 224 (71) | 0.88 (0.81–0.96) |
| Prior antibiotics | |||
| Yes | 214 | 153 (72) | 0.90 (0.78–1.04) |
| No | 138 | 105 (76) | — |
| Prior massage | |||
| Yes | 258 | 185 (72) | 0.93 (0.79–1.09) |
| No | 95 | 74 (78) | — |
| Study | |||
| Study A | 234 | 164 (70) | — |
| Study B | 126 | 98 (78) | 1.09 (0.96–1.24) |
CI, confidence interval.
Data are pooled across studies. For study B, success is defined as the absence of clinical signs (epiphora, mucous discharge and increased tear film) at the 6-month visit and no prior reoperation. For study A, success is defined as the absence of clinical signs at the 1-month visit (reoperation was not allowed). Dashes indicate reference levels.
Percentages are not corrected for correlation of eyes in subjects with both eyes in the study.
Relative risk compares risk between the specified level and reference level. Relative risks and 95% CIs are from Poisson regression models using the factor of interest, laterality, number of baseline clinical signs of NLDO, and study as covariates and use generalized estimating equations to account for the intereye correlation between eyes from subjects who have both eyes in the study.
Adjusted relative risk per additional month of age at surgery is 0.99 (0.95–1.03).
Clinical signs evaluated were epiphora, mucous discharge and increased tear lake. 91% of eyes with one clinical sign had increased tear film alone.