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. 2014 Mar;184(3):584–591. doi: 10.1016/j.ajpath.2013.11.023

Figure 1.

Figure 1

Histomorphological features and immunophenotype of a case of primary urethral clear-cell adenocarcinoma. A and B: H&E and IHC staining for CK7 (C) and PAX8 (D). A: The tumor showed a predominantly papillary architecture with fibrovascular septae and cores. B: Tumor cells had vacuolated, clear cytoplasm and basally located pleomorphic nuclei without prominent nucleoli. IHC demonstrated that tumor cells diffusely and strongly expressed CK7 in a membranous pattern (C) and PAX8 in a nuclear manner (D). Original magnification: ×100 (A); ×400 (B–D).