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. Author manuscript; available in PMC: 2014 May 1.
Published in final edited form as: J Hepatol. 2013 Jan 16;58(5):949–955. doi: 10.1016/j.jhep.2013.01.003

Table 5.

Comparison of median fecal bile acid values pre and post rifaximin

Median values in μg/100 mg dry stool Prospective trial
Pre rifaximin (n=6) Post-rifaximin (n=6)
Total Bile Acids 581 526
Primary
CA 21.5 39.3*
CDCA 2.6 19.2*
Secondary
LCA 113.9 118.9
DCA 377.6 354.2
Secondary/Primary Ratios
LCA/CDCA 20.1 3.4*
DCA/CA 13.9 2.5
LCA+DCA / CDCA+CA 17.5 2.5*

p<0.05 in this open-label trial of rifaximin in early cirrhotic patients, there was a net decrease in the secondary/primary BA ratio after rifaximin using the Wilcoxon matched-pairs test.

CA: cholic acid, CDCA: chenodeoxycholic acid, LCA: lithocholic acid, DCA: deoxycholic acid