Table 1. Descriptive Statistics for Age, Segmentation Agreement, Everyday Memory, and Brain Volume.
Variable | CDR score = 0 | CDR score = 0.5 | CDR score = 1 | |||||||||
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M | Median | Range | d (CDR = 0 vs. 0.5)a | M | Median | Range | d (CDR =0.5 vs. l)a | M | Median | Range | d (CDR = 0 vs. l)a | |
Age (years) | 74.65 | 75.00 | 65–86 | −0.55 | 77.83 | 78.00 | 66–86 | 0.05 | 77.55 | 78.00 | 63–90 | −0.47 |
Segmentation agreement | ||||||||||||
Breakfast | .38 | .34 | .24–.58 | 0.20 | .36 | .33 | .07–.59 | 0.62 | .28 | .29 | .00–.46 | 0.84 |
Library | .45 | .45 | .27–.61 | 0.72 | .39 | .40 | .18–.64 | 0.72 | .30 | .32 | .05–.52 | 1.33 |
Party | .43 | .42 | .19–.68 | 0.59 | .36 | .35 | .03–.59 | 0.78 | .28 | .29 | .04–.40 | 1.36 |
Recall | ||||||||||||
Breakfast | 22.18 | 21.00 | 1–61 | 0.88 | 13.10 | 13.00 | 0–31 | 1.26 | 4.24 | 3.00 | 0–23 | 1.94 |
Library | 13.03 | 12.50 | 1–34 | 0.64 | 6.78 | 6.00 | 0–24 | 1.29 | 1.81 | 2.00 | 0–10 | 1.86 |
Party | 26.65 | 22.50 | 1–74 | 0.77 | 13.24 | 10.00 | 0–57 | 1.00 | 2.76 | 1.00 | 0–12 | 1.65 |
Recognition | ||||||||||||
Breakfast | .71 | .70 | .40–.90 | 0.50 | .65 | .65 | .30–.90 | 1.09 | .50 | .50 | .30–.80 | 1.60 |
Library | .77 | .80 | .20–.95 | 0.33 | .72 | .70 | .35–1.0 | 1.12 | .55 | .53 | .25–.80 | 1.58 |
Party | .88 | .90 | .20–.1.0 | 0.66 | .78 | .80 | .40–1.0 | 1.26 | .60 | .60 | .40–.90 | 1.90 |
Order memory (errors) | ||||||||||||
Breakfast | 0.66 | 0.33 | 0.00–4.5 | −0.74 | 1.41 | 1.00 | 0.00–4.5 | −1.44 | 3.24 | 3.00 | 0.83–5.5 | −2.20 |
Library | 1.48 | 1.50 | 0.00–4.3 | −0.99 | 2.58 | 2.50 | 0.50–4.5 | −1.05 | 3.70 | 3.83 | 1.0–5.0 | −2.21 |
Party | 0.12 | 0.00 | 0.00–0.83 | −0.37 | 0.23 | 0.17 | 0.00–1.8 | −1.36 | 1.54 | 1.33 | 0.00–4.7 | −1.51 |
Volume (mm3) | ||||||||||||
Entorhinal cortex | 3,926 | 3,927 | 2,821–5,203 | 0.71 | 3,469 | 3,397 | 2,084–4,597 | 1.38 | 2,544 | 2,574 | 1,615–3,721 | 2.18 |
Hippocampus | 7,526 | 7,528 | 5,836–9,056 | 1.18 | 6,491 | 6,316 | 5,001–8,403 | 0.99 | 5,671 | 5,685 | 4,730–6,734 | 2.71 |
Parahippocampal gyrus | 3,662 | 3,645 | 2,814–4,693 | 0.34 | 3,478 | 3,473 | 2,052–4,542 | 0.87 | 2,987 | 2,965 | 1,871–3,846 | 1.38 |
DLPFC | 27,294 | 27,304 | 23,511–32,853 | 0.46 | 25,951 | 25,467 | 19,441–31,890 | −0.15 | 26,382 | 26,385 | 22,659–32,247 | 0.35 |
Note: CDR = Clinical Dementia Rating scale (Morris, 1993); DLPFC = dorsolateral prefrontal cortex.
The effect size between the two indicated CDR groups was calculated using Cohen's d