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. 2014 Mar;184(3):686–696. doi: 10.1016/j.ajpath.2013.11.032

Figure 3.

Figure 3

Differential skin angiogenesis among WT, kPhd2KO, kDKO, and kTKO mice without operation by FAL. A: Paw redness in kDKO and kTKO, but not WT and kPhd2KO, mice 4 weeks after tamoxifen treatment. B: Laser Doppler imaging of paws. C: Whole-mount anti-CD31 (green) and anti-CD11b (red) double IF staining of the dermal layer of skin tissues. D: Blood perfusion values in different groups of mice relative to WT, the latter of which was set at onefold. E: Number of CD31+ vascular branching points per high power field. F: CD11b+ cells per unit area. n = 6 (A, B, and D); n = 3 (C, E, and F). ∗P < 0.05, ∗∗P < 0.01 (D–F) by Student's t-tests. Scale bars: 100 μm (C).