Table 1.
Micro-CT Analyses in D2J Mutant and D2J/Gpnmb+ Wild-Type Mice
| Age (wk) | Genotype | Tb.Th (μm) | B.S/TV (mm2/mm3) | B.S/BV (mm2/mm3) |
|---|---|---|---|---|
| 4 | D2J/Gpnmb+ | 17.78 ± 0.39 | 8.27 ± 0.18 | 111.7 ± 2.23 |
| D2J | 16.37 ± 0.34∗ | 7.38 ± 0.27∗ | 121 ± 2.83∗ | |
| 8 | D2J/Gpnmb+ | 23.87 ± 0.81 | 19.36 ± 1.61 | 84.75 ± 3.14 |
| D2J | 17.03 ± 0.36∗∗∗∗ | 9.8 ± 0.24∗∗∗∗ | 117.8 ± 2.51∗∗∗∗ | |
| 16 | D2J/Gpnmb+ | 21.22 ± 0.67 | 12.52 ± 0.6 | 99.07 ± 3.07 |
| D2J | 17.12 ± 1.23∗∗ | 10.07 ± 0.47∗∗ | 119.0 ± 78∗∗ |
Data are expressed as means ± SEM.
∗P < 0.05, ∗∗P < 0.01, and ∗∗∗∗P < 0.0001 versus wild type.
B.S/TV, bone surface per tissue volume; B.S/BV, bone surface per bone volume; Tb.Th, trabecular thickness.