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Representative pressure-volume loops before and after MI model creation. Representative pressure-volume loops demonstrating pathological changes from baseline to 2 weeks after MI. The decrease in the slope of the end systolic pressure-volume relationship (ESPVR) curve (straight arrow) indicates considerable contractility impairment, and the steeper slope of the end diastolic pressure-volume relationship (EDPVR) curve (curved arrow) reflects the increase in ventricular stiffness.
