Table 1.

Antiviral activity of the extract and fractions of Hedera helix against EV71 C3

Test material	CC50a	EC50b	TIc
Hedera helix 30% EtOH extract	>50	6.58 ± 0.11	7.59
100% H2O	>50	NDd	-
20% MeOH	>50	25.23 ± 4.93	1.98
40% MeOH	>50	7.92 ± 1.44	6.31
60% MeOH	>50	2.75 ± 1.05	18.18
80% MeOH	>50	38.22 ± 4.13	1.31
100% MeOH	31.03	NDd	-

Results are presented as the mean EC₅₀ values ± SD obtained from three independent experiments carried out in triplicate.

^aConcentration required to reduce cell growth by 50% (μg/ml).

^bConcentration required to inhibit virus-induced CPE by 50% (μg/ml).

^cTherapeutic index=CC₅₀/EC₅₀.

^dNot determined.