Table 1.

Inhibitory effects of ginsenosides SF, Rk₃, Rg₆, and Rs₄ on the TNF-α-induced NF-κB transcriptional activity and iNOS promoter activity in HepG2 and SK-Hep1 hepatocyte-derived cells

Ginsenoside or Compound	IC50 (μM)*
	HepG2		SK-Hep1
	NF-κB	iNOS	NF-κB	iNOS
Ginsenoside SF	33.86 ± 4.14	13.07 ± 0.64	18.17 ± 0.69	11.26 ± 0.87
Ginsenoside Rk3	14.24 ± 1.30	9.83 ± 0.06	15.32 ± 0.29	6.02 ± 0.37
Ginsenoside Rg6	29.34 ± 2.22	19.45 ± 0.55	25.12 ± 1.04	10.36 ± 0.69
Ginsenoside Rs4	12.44 ± 2.01	10.01 ± 1.21	11.98 ± 0.85	6.92 ± 0.65
Apigenin**	1.64 ± 0.19	4.45 ± 0.24	3.60 ± 0.21	3.63 ± 0.17

^*Results are the means ± SEM of three independent experiments performed in triplicate.

^**Positive control. apigenin