. Author manuscript; available in PMC: 2014 Nov 15.

Published in final edited form as: J Chromatogr B Analyt Technol Biomed Life Sci. 2013 Sep 8;939:23–31. doi: 10.1016/j.jchromb.2013.09.004

Table 5.

Stability in plasma.

	% of original value
	Room temp.		Freeze/thaw x1		Freeze/thaw x3
	Low	High	Low	High	Low	High
Buprenorphine	101.3 ± 14.1	102.1 ± 9.1	113.0 ± 10.3	104.4 ± 10.6	106.0 ± 6.6	101.5 ± 12.6
Norbuprenorphine	99.1 ± 9.9	100.6 ± 1.4	109.3 ± 14.4	102.7 ± 5.2	101.4 ± 15.0	101.4 ± 6.3
Buprenorphine glucuronide	108.4 ± 8.2	108.9 ± 7.4	116.9 ± 10.9	111.5 ± 6.6	114.8 ± 10.3	112.8 ± 4.9
Norbuprenorphine glucuronide	114.2 ± 6.7	102.3 ± 14.2	105.1 ± 13.5	102.3 ± 8.5	116.7 ± 9.4	103.0 ± 5.6

Results are the mean ± standard deviation (N = 3). Low concentration was 0.01 ng/mL and high concentration was 10 ng/mL.