. Author manuscript; available in PMC: 2014 Nov 15.

Published in final edited form as: J Chromatogr B Analyt Technol Biomed Life Sci. 2013 Sep 8;939:23–31. doi: 10.1016/j.jchromb.2013.09.004

Table 6.

Stability in urine.

	% of original value
	Room temp		Freeze/thaw x1		Freeze/thaw x3
	Low	High	Low	High	Low	High
Buprenorphine	87.7 ± 1.9	101.1 ± 5.9	92.9 ± 4.3	95.5 ± 3.4	94.1 ± 13.7	97.7 ± 9.8
Norbuprenorphine	109.8 ± 1.1	104.1 ± 7.0	82.5 ± 7.3	89.4 ± 8.4	101.8 ± 5.6	92.1 ± 10.8
Buprenorphine glucuronide	108.7 ± 3.5	82.4 ± 8.5	101.3 ± 11.6	100.4 ± 11.6	97.3 ± 7.1	96.6 ± 8.8
Norbuprenorphine glucuronide	101.9 ± 10.1	86.2 ± 11.5	105.6 ± 4.8	93.5 ± 8.6	101.5 ± 8.3	104.1 ± 10.6

Results are the mean ± standard deviation (N = 3). Low concentration was 0.06 ng/mL and high concentration was 60 ng/mL.