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. 2014 Feb 20;10:46. doi: 10.1186/1746-6148-10-46

Table 2.

Relative mRNA concentrations of ER stress-induced genes in the liver of Holstein cows at 3 wk antepartum and 1, 5 and 14 wk postpartum 1

Gene 2 3 wk antepartum (n = 13) 1 wk postpartum (n = 13) 5 wk postpartum (n = 13) 14 wk postpartum (n = 13)
ATF4
1.00 ± 0.25a
3.14 ± 0.25c
2.08 ± 0.26b
1.65 ± 0.24b
BAK1
1.00 ± 0.29a
2.10 ± 0.30b
1.56 ± 0.29ab
1.59 ± 0.28ab
BAX
1.00 ± 0.36a
3.02 ± 0.39b
1.98 ± 0.35ab
1.52 ± 0.35a
CASP3
1.00 ± 0.31a
2.54 ± 0.27b
2.07 ± 0.26b
1.71 ± 0.26ab
CASP8
1.00 ± 0.25a
2.48 ± 0.24b
1.88 ± 0.23ab
1.73 ± 0.23ab
CASP9
1.00 ± 0.37a
2.45 ± 0.35b
1.89 ± 0.34ab
1.84 ± 0.36ab
DDIT3
1.00 ± 0.17a
1.86 ± 0.17b
1.58 ± 0.17ab
1.41 ± 0.17ab
DNAJC3
1.00 ± 0.15a
1.89 ± 0.17b
1.49 ± 0.17ab
1.43 ± 0.15ab
EDEM1
1.00 ± 0.21a
1.70 ± 0.21b
1.69 ± 0.20b
1.25 ± 0.22ab
HERPUD1
1.00 ± 0.45a
3.96 ± 0.37b
2.27 ± 0.43a
1.66 ± 0.38a
HSPA5
1.00 ± 0.29a
2.74 ± 0.27b
1.64 ± 0.26a
1.41 ± 0.24a
PDIA4
1.00 ± 0.25a
1.92 ± 0.28b
1.34 ± 0.24ab
1.23 ± 0.25ab
WARS
1.00 ± 0.35a
2.03 ± 0.31ab
2.31 ± 0.29b
1.93 ± 0.30ab
XBP1 (unspliced) 1.00 ± 0.25a 3.14 ± 0.25c 2.08 ± 0.26b 1.65 ± 0.24b

1mRNA concentrations of genes are expressed relative to the mRNA abundance at 3 wk antepartum.

2Abbreviations of gene names: see Table 1.

Values are means ± SEM.

a,b,cMeans without common superscripts differ significantly (P < 0.05).