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. 2014 Feb 20;10:46. doi: 10.1186/1746-6148-10-46

Table 3.

Relative mRNA concentrations of genes associated with DNA damage, DNA repair and cell cycle in the liver of Holstein cows at 3 wk antepartum and 1, 5 and 14 wk postpartum 1

Gene 2 3 wk antepartum (n = 13) 1 wk postpartum (n = 13) 5 wk postpartum (n = 13) 14 wk postpartum (n = 13)
ATM
1.00 ± 0.21a
2.29 ± 0.21b
1.94 ± 0.35ab
1.81 ± 0.26ab
BRCA1
1.00 ± 0.22
1.71 ± 0.27
1.59 ± 0.20
1.33 ± 0.23
HSBP1
1.00 ± 0.23a
3.04 ± 0.42b
2.14 ± 0.24ab
1.65 ± 0.34a
HSPA8
1.00 ± 0.24a
2.01 ± 0.24b
1.78 ± 0.23ab
1.22 ± 0.27a
MSH2
1.00 ± 0.20a
4.04 ± 0.61b
1.81 ± 0.22a
1.41 ± 0.23a
RPS9
1.00 ± 0.20a
3.68 ± 0.28c
2.23 ± 0.29b
1.64 ± 0.31ab
XRCC5 1.00 ± 0.21a 3.69 ± 0.54c 2.35 ± 0.27b 1.43 ± 0.26a

1mRNA concentrations of genes are expressed relative to the mRNA abundance at 3 wk antepartum.

2ATM = ataxia telangiectasia mutated; BRCA1 = breast cancer 1, early onset; HSBP1 = heat shock factor binding protein 1; HSPA8 = heat shock 70 kDa protein 8; MSH2 = mutS homolog 2; RPS9 = ribosomal protein S9; XRCC5 = X-ray repair cross-complementing protein 5-like.

Values are means ± SEM.

a,b,cMeans without common superscripts differ significantly (P < 0.05).