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. 2013 Nov 27;42(4):2245–2256. doi: 10.1093/nar/gkt1236

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© The Author(s) 2013. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 6. — Nucleosome occupancy of the TFF1 enhancer is regulated by MLL1. (A and B) Nucleosome occupancy at the TFF1 promoter and enhancer was analyzed by NOMe-seq in siNS transfected or MLL1-depleted MCF-7 cells. Blue circles represent GpC sites of the DNA (unfilled blue circles represent GpC sites that are inaccessible to GpC methyltransferase; teal-filled circles represent cytosines accessible to GpC methyltransferase). Pink bars represent regions of inaccessibility large enough to accommodate a nucleosome (∼150 bp).