Table 1.
Summary statistics of predicted combinatorial TF patterns in four cell types
| Statistics | GM12878 | H1 | HepG2 | K562 |
|---|---|---|---|---|
| Number of predicted patterns | 320 | 62 | 194 | 300 |
| Number of supported pairwise interactions (%) | 109 (5.8) | 80 (10.8) | 68 (7.2) | 166 (8.0) |
| Number of supported patterns (P-value) | 183 (0) | 21 (5.9E-9) | 35 (4.0E-9) | 100 (8.2E-59) |
| Number of TF pairs, triplets and quadruplets | 38, 210, 72 | 61, 1, 0 | 111, 79, 4 | 137, 154, 9 |
| Number of TFs in patterns (%) | 22 (35.5) | 21 (53.9) | 31 (70.4) | 41 (63.1) |
| Number of enhancers in patterns (%) | 7076 (56) | 13391 (64.6) | 13838 (67.7) | 9073 (30.1) |
A TF set is considered to be supported by known TF interactions if any of the pairwise interactions between two TFs in the TF set was supported by known TF interactions. P-values are calculated using binomial distribution.