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. Author manuscript; available in PMC: 2014 Feb 27.
Published in final edited form as: JAMA Intern Med. 2013 Oct 28;173(19):1788–1796. doi: 10.1001/jamainternmed.2013.9245

Table 7.

A patient’s risk of thyroid cancer based on the ultrasound appearance of the thyroid gland and the characteristics of any nodules identified.

Individual or Combination of Ultrasound Cancers per 1000 patients (95% CI)
Lowest Risk
 Thyroid has only nodule(s) that are entirely cystic 0.32 (0.1–1.8)

 Homogenous Thyroid 0.63 (0.1–1.9)

Very low
 Thyroid has no solid nodule(s), no nodule>2 cm, and no nodule with Microcalcification 2 (1–3)

 Thyroid has no nodule(s) with 2 or more suspicious characteristic 5 (4–6)

Low
 Thyroid has at least one nodule that is entirely solid or > 2cm or has microcalcification 18 (15–22)

Moderate
 Thyroid has at least one nodule with 2 suspcious characteristics 62 (47–80)

 Thyroid has at least one nodule with Microcalcifications 82 (59–110)

 Thyroid has at least one nodule with Microcalcifications or is both Solid and > 2cm 58 (44–75)

High
 Thyroid has at least one entirely solid nodule with microcalcification and a size greater than 2 cm 960 (803–991)