Table 1.
Expression a of microdomain-forming proteins mRNA in NSCLC
| |
Stomatin (n = 48) |
Flotillin-1 (n = 47) |
Caveolin-1 (n = 48) |
|||||
|---|---|---|---|---|---|---|---|---|
| up | equal | down | up | equal | down | equal | down | |
| NSCLC |
3 |
8 |
37 |
3 |
11 |
33 |
2 |
46 |
| Adenocarcinomas |
2 |
4 |
16 |
2 |
6 |
13 |
1 |
21 |
| Squamous cell carcinomas |
1 |
4 |
21 |
1 |
5 |
20 |
1 |
25 |
| Tumor size |
|
|
|
|
|
|
|
|
| T1-T2 |
3 |
3 |
24 |
2 |
6 |
21 |
1 |
29 |
| T3-T4 |
0 |
5 |
13 |
1 |
5 |
12 |
1 |
17 |
| Lymph node status |
|
|
|
|
|
|
|
|
| N0 |
1 |
3 |
16 |
0 |
7 |
12 |
0 |
20 |
| N+ |
2 |
5 |
21 |
3 |
4 |
21 |
2 |
26 |
| Clinical stage |
|
|
|
|
|
|
|
|
| I-II |
2 |
2 |
22 |
1 |
6 |
18 |
1 |
25 |
| III-IV |
1 |
6 |
15 |
2 |
5 |
15 |
1 |
21 |
| Degree of differentiation |
|
|
|
|
|
|
|
|
| High |
1 |
0 |
1 |
0 |
0 |
1 |
0 |
2 |
| Moderate |
1 |
5 |
24 |
2 |
6 |
22 |
1 |
29 |
| Low | 1 | 3 | 12 | 1 | 5 | 10 | 1 | 15 |
aup – higher gene expression in tumors compared with normal tissue samples.
down – lower gene expression in tumors compared with normal tissue samples.
equal – no significant difference in gene expression in tumors versus normal tissue samples.