Table 4.
Severe OCs | Perinatal asphyxia | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
t | p | adj p | B | (s.e.) | t | p | adj p | B | (s.e.) | |
Left hippocampus | ||||||||||
Non-psychotic BD | −2.49 | 0.019 | 0.057 | −386.2 | (155.0) | −1.81 | 0.082 | 0.246 | −333.2 | (178.0) |
Psychotic BD | −0.09 | 0.93 | 1 | −11.0 | (124.6) | −0.08 | 0.936 | 1 | −12.3 | (153.2) |
Right hippocampus | ||||||||||
Non-psychotic BD | −3.25 | 0.003 | 0.009 | −485.6 | (149.5) | −2.60 | 0.015 | 0.045 | −449.0 | (173.0) |
Psychotic BD | −0.77 | 0.445 | 1 | −82.4 | (106.8) | 0.06 | 0.95 | 1 | 8.3 | (132.2) |
Left amygdala | ||||||||||
Non-psychotic BD | −1.19 | 0.244 | 0.732 | −85.6 | (71.8) | −0.94 | 0.359 | 1 | −74.2 | (79.4) |
Psychotic BD | −1.95 | 0.058 | 0.168 | −107.3 | (55.1) | −2.69 | 0.010 | 0.030 | −175.5 | (65.4) |
Right amygdala | ||||||||||
Non-psychotic BD | −0.27 | 0.791 | 1 | −22.6 | (83.0) | 0.30 | 0.764 | 1 | 27.5 | (90.8) |
Psychotic BD | −1.15 | 0.257 | 0.771 | −72.8 | (63.4) | −2.26 | 0.029 | 0.087 | −168.8 | (74.9) |
Left lateral ventricle | ||||||||||
Non-psychotic BD | 0.23 | 0.871 | 1 | 389.3 | (1162.1) | −0.29 | 0.772 | 1 | −531.5 | (1818.8) |
Psychotic BD | −1.65 | 0.107 | 0.321 | −2172.7 | (1319.6) | −0.76 | 0.442 | 1 | −1288.1 | (1661.5) |
Right lateral ventricle | ||||||||||
Non-psychotic BD | 0.90 | 0.377 | 1 | 1303.2 | (1450.6) | 0.52 | 0.610 | 1 | 827.9 | (1604.6) |
Psychotic BD | −0.77 | 0.447 | 1 | −986.2 | (1286.2) | −0.29 | 0.776 | 1 | −456.3 | (1590.9) |
Severe OCs, Severe hypoxia-related obstetric complications; BD, bipolar disorder; adj p, adjusted p values after Bonferroni correction; s.e., standard error.
Linear regression analyses controlled for effects of age, sex and intracranial volume within each diagnostic group.