Table 1.
Characteristics of the total genetic disorder sample
| Genetic disorder |
N |
Age (months) |
ASD |
ADI-R scores per domain and total scores |
IQ | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Total | Female | Male | Yes | No | I | II | III | Total | |||
| 22q11DS |
90 |
42 |
48 |
162.5 ± 33.6 |
40 |
50 |
9.8 ± 6.4 |
7.7 ± 4.8 |
2.5 ± 2.2 |
20.0 ± 12.0 |
67.0 ± 14.1 |
| Down’s |
21 |
16 |
5 |
169.1 ± 32.6 |
6 |
15 |
7.2 ± 4.4 |
6.8 ± 3.8 |
3.2 ± 2.0 |
17.2 ± 8.6 |
49.5 ± 11.9 |
| PWS |
88 |
48 |
40 |
191.9 ± 141.0 |
20 |
68 |
7.9 ± 5.1 |
5.7 ± 4.5 |
2.8 ± 2.0 |
16.3 ± 10.1 |
70.9 ± 16.3 |
| SMC15 |
22 |
8 |
14 |
161.4 ± 103.6 |
19 |
3 |
15.6 ± 6.0 |
13.6 ± 5.5 |
6.5 ± 2.4 |
35.7 ± 12.2 |
51.0 ± 19.0 |
| TSC |
50 |
31 |
19 |
126.2 ± 74.0 |
22 |
28 |
12.0 ± 9.0 |
9.6 ± 6.8 |
3.7 ± 3.3 |
25.2 ± 17.9 |
69.3 ± 27.4 |
| XXY |
51 |
0 |
51 |
145.4 ± 41.4 |
16 |
35 |
8.5 ± 6.0 |
8.8 ± 5.4 |
2.3 ± 2.1 |
19.6 ± 12.0 |
80.4 ± 13.9 |
| Total |
322 |
145 |
177 |
|
123 |
199 |
|
|
|
|
|
| Average | 162.7 ± 89.8 | 9.6 ± 6.7 | 8.0 ± 5.6 | 3.1 ± 2.5 | 20.6 ± 13.4 | 68.6 ± 19.2 | |||||
Data provided are mean values and, if applicable, standard error of the means. ADI-R domains: I, qualitative abnormalities in reciprocal social interaction; II, qualitative abnormalities in communication; and III, restricted, repetitive and stereotyped patterns of behavior. 22q11DS, 22q11.2 deletion syndrome; ADI-R, Autism Diagnostic Interview-Revised; ASD, autism spectrum disorder; Down’s, Down’s syndrome; PWS, Prader-Willi syndrome; SMC15, supernumerary marker chromosome 15; TSC, tuberous sclerosis complex; XXY, Klinefelter syndrome.