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. 2014 Feb 25;14:76. doi: 10.1186/1472-6882-14-76

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Copyright © 2014 Kumar et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Paederia Foetida Linn. leaves extract effect on heart histopathology in normal and STZ induced diabetic rats. (A) Normal control: Normal histopathology (B) Diabetic control: Display increased interstitial space and distort the intercalated disc (yellow arrow). (C)PF I (100 mg/kg): Display less interstitial space and intercalated disc (yellow arrow). (D)PF II (250 mg/kg): PF treated drug display only space in intercalated disc (yellow arrow). (E)PF III (500 mg/kg): Did not display any changes of the heart histopathology (F) Glibenclamide (10 mg/kg): Histopathology similar to the normal group. The samples were obtained from the same liver anatomical regions. For each group, 6 rats were examined and 50 pictures were taken. Original magnification, 10×.