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. 2014 Feb 21;10:15. doi: 10.1186/1744-8069-10-15

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Copyright © 2014 Hayashi et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Retigabine or ICA-27243 reduces exploratory behavior. Exploratory behavior in rats was quantified 30 min after the treatment with retigabine (A) and ICA-27243 (B) at 1, 3, 10 or 30 mg/kg and 3, 10, 30 or 100 mg/kg, respectively. Each data was presented as the mean ± S.E.M., each mean showed summation for 10 min in 6 rats. *p < 0.05 vs vehicle.